A Beginner's Guide to Muslim Bioethics

Too interesting to relegate to the link sidebar; via Wired. Excerpt, from a Brown University anthropologist:

Of course there are always people who are extremists and who take absolutist positions -- but as a scholarly orthodox tradition, Islamic scholars have generally incorporated social contingencies into their opinions about the permissibility of modern practices, especially with the legal tool of "maslaha" -- which is a calculus of weighing particular benefits against risks (measured both socially and spiritually) [...].

The detailed breakdown provided by a bioethicist from King Faisal University (Saudi Arabia) is also highly educational. Although its phrasing is on the strict side, the actual range of technologies permitted is surprising.

How to: bioengineer mosquitoes to stop spread of disease

Via Wired, I learned about Oxitec, a UK company making improvements on the 'sterile insect technique' currently used for some types of for pest management. In standard SIT, radiation-sterilized male mosquitoes are released into the wild, where they'll mate with wild-type females but cause the females' eggs to be non-viable. This has worked okay, but is not that scalable because the radiation step is tricky and tends to deplete your stock of male mosquitoes. In Oxitec's technique, the males are genetically altered to be dependent on tetracycline, which they are fed until release into the wild. Their offspring will also be tetracycline-dependent, and so will die before reaching reproductive maturity. Ultimately, this is all in the service of eradicating mosquito-borne diseases like Dengue fever, malaria, and so on.

Like many experiments in genetic engineering, this has the potential to be a pretty environmentally-friendly way to do the job (compared to, say, massive use of pesticides) but like most people I have a hard time shaking the feeling that somehow, it could all go terribly wrong. I'm inclined to call this vague sense of impending bio-engineered doom "Jurassic Park Syndrome."

News on the food regulation front

Yesterday the Soil Association (the British organization in charge of certifying organic foods) announced that cosmetics, food and clothing made using nanoparticles will not be classed as organic in the UK.

Today the FDA declared that meat and dairy from cloned animals is safe to eat and will not require any additional labeling in the US. The Wired article notes:

Food producers say they're not about to put cloned meat on American dinner plates, as the procedure is too expensive and inefficient, and a third of U.S. adults say they won't eat cloned meat regardless of its approval. Instead, farmers will purchase cloned animals to serve as breeding stock for their entire herds.

I'm not sure yet how I feel about cloned meat in any form, but I'm disturbed that if/when it arrives, it won't be labeled similarly to the way irradiated meat must be labeled. I expect that we're in for another category of voluntary certification to go alongside 'organic' and 'natural,' capturing this concern about bioengineered food. Here's a question -- how come the dairy industry asked the FDA in the 1990's to allow them to voluntarily label their products rBGH-free, while the meat industry appears to be resisting the mandatory irradiated-meat labels?

Colorado biotech is selling, Big Pharma is buying

Colorado biotech blogger (and my work associate) Adam Rubenstein got some press over the weekend in the Denver Post, discussing drug development in Colorado. Aside from his day job, Adam manages the Colorado Life Science Deal Flow and OnBioVC blogs.